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Biblioteca(s): |
Embrapa Unidades Centrais. |
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Data corrente: |
18/10/2018 |
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Data da última atualização: |
18/10/2018 |
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Autoria: |
DIAS, D. P. M.; SOUSA, S. S.; MOLEZINI, F. A.; FERREIRA, H. S. D.; CAMPOS, R. de. |
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Afiliação: |
Deborah P. M. Dias, Centro Universitário Barão de Mauá; Samuel S. Sousa, Centro Universitário Barão de Mauá; Flávia A. Molezini, Centro Universitário Barão de Mauá; Henrique S. D. Ferreira, Centro Universitário Barão de Mauá; Reinaldo de Campos, Equine Center/Jockey Club de São Paulo. |
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Título: |
Efficacy of faecal microbiota transplantation for treating acute colitis in horses undergoing colic surgery. |
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Ano de publicação: |
2018 |
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Fonte/Imprenta: |
Pesquisa Veterinária Brasileira, Brasília, DF, v. 38, n 8, p. 1564-1569, agosto 2018 |
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Idioma: |
Inglês |
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Notas: |
Título em português: Eficácia do transplante de microbiota fecal no tratamento da colite aguda em equinos submetidos a cirurgia de cólica. |
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Conteúdo: |
The report describes the outcome of four horses treated with homologous faecal microbiota transplantation (FMT) for acute colitis. The horses developed diarrhoea and fever a few days after a laparotomy to treat gastrointestinal disease. Medical records were reviewed to identify the horses as well as to describe the primary intestinal disease, clinical findings, surgical intervention, FMT protocol, outcome and follow-up of each case. The principle of the efficacy of FMT is that restoration of a balanced nonpathogenic bacterial population may be the primary defence mechanism against colonization of pathogenic bacteria in the equine gastrointestinal tract. The FMT did not produce adverse reactions and was demonstrated to rapidly control diarrhoea and fever in all cases. A complete resolution of clinical sings was observed within 24 hours when horses were given a single FMT. Further clinical studies are necessary to determine the optimal preparation and to reinforce the efficacy of FMT for treating acute colitis following colic surgery. The technique has the potential to be an inexpensive, safe and highly efficient tool for the prevention and treatment of infectious gastrointestinal diseases in horses, preventing antimicrobial resistance. |
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Palavras-Chave: |
Bacterioterapia; Diarrohea; Intestinal microbiota; Microbiota; Microbiota intestinal; Microbiota transplantation. |
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Thesagro: |
Cirurgia; Colite; Diarréia; Eqüino; Tratamento. |
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Thesaurus NAL: |
Colitis; Horses; Surgery. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/184706/1/Efficacy-of-faecal-microbiota-transplantation.pdf
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Marc: |
LEADER 02381naa a2200349 a 4500
001 2097755
005 2018-10-18
008 2018 bl uuuu u00u1 u #d
100 1 $aDIAS, D. P. M.
245 $aEfficacy of faecal microbiota transplantation for treating acute colitis in horses undergoing colic surgery.$h[electronic resource]
260 $c2018
500 $aTítulo em português: Eficácia do transplante de microbiota fecal no tratamento da colite aguda em equinos submetidos a cirurgia de cólica.
520 $aThe report describes the outcome of four horses treated with homologous faecal microbiota transplantation (FMT) for acute colitis. The horses developed diarrhoea and fever a few days after a laparotomy to treat gastrointestinal disease. Medical records were reviewed to identify the horses as well as to describe the primary intestinal disease, clinical findings, surgical intervention, FMT protocol, outcome and follow-up of each case. The principle of the efficacy of FMT is that restoration of a balanced nonpathogenic bacterial population may be the primary defence mechanism against colonization of pathogenic bacteria in the equine gastrointestinal tract. The FMT did not produce adverse reactions and was demonstrated to rapidly control diarrhoea and fever in all cases. A complete resolution of clinical sings was observed within 24 hours when horses were given a single FMT. Further clinical studies are necessary to determine the optimal preparation and to reinforce the efficacy of FMT for treating acute colitis following colic surgery. The technique has the potential to be an inexpensive, safe and highly efficient tool for the prevention and treatment of infectious gastrointestinal diseases in horses, preventing antimicrobial resistance.
650 $aColitis
650 $aHorses
650 $aSurgery
650 $aCirurgia
650 $aColite
650 $aDiarréia
650 $aEqüino
650 $aTratamento
653 $aBacterioterapia
653 $aDiarrohea
653 $aIntestinal microbiota
653 $aMicrobiota
653 $aMicrobiota intestinal
653 $aMicrobiota transplantation
700 1 $aSOUSA, S. S.
700 1 $aMOLEZINI, F. A.
700 1 $aFERREIRA, H. S. D.
700 1 $aCAMPOS, R. de
773 $tPesquisa Veterinária Brasileira, Brasília, DF$gv. 38, n 8, p. 1564-1569, agosto 2018
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Embrapa Unidades Centrais (AI-SEDE) |
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